People

Graduate Students

 Andrew Vo: I am currently completing my doctoral studies in Psychology (Behavioural and Cognitive Neuroscience) under the direction of Dr. Penny MacDonald at the Brain and Mind Institute, Department of Psychology, University of Western Ontario.  I am interested in the role of dopamine and the striatum in different aspects of cognition.  My dissertation explores how cognitive functions mediated by the ventral striatum evolve with the progression of Parkinson’s disease and how dopaminergic therapy might address these symptoms.  We use behavioural, psychopharmacological, and functional MRI in both patients with Parkinson’s disease and healthy volunteers to test our hypotheses.
4W9A1280_webAbdullah Al-Jaja: My name is Abdullah Al Jaja. I am completing my PhD in neuroscience under the co-supervision of Dr. Penny MacDonald (PI) and Dr. Jessica Grahn. My research investigates several aspects of Parkinson’s disease (PD). From a molecular level, we are looking at the genetic polymorphisms that increase or decrease dopaminergic signaling in the striatum. In another study, I am examining the effect of cognitive training and anxiety reduction on freezing of gait in PD patients. And lastly my third project investigate the changes in brain EEG activity and neural connectivity following auditory and visual processing. Globally, my projects aim to increase and strengthen our understanding of the dorsal and ventral striatum in PD.  
4W9A0387_web2Nicholas Handfield-Jones: I defended my Master’s of Neuroscience under the co-supervision of Dr. Penny MacDonald (PI), Dr. Ali Khan, and Dr. Adrian Owen. My work focused primarily on understanding the neuroanatomy and neurocircuitry of the substantia nigra pars compacta and the ventral tegmental area, two important midbrain nuclei involved in a wide range of behaviours and diseases. I used magnetic resonance imaging data from the Human Connectome Project to map out these important brain structures. Come Fall 2019, I will continue in the MacDonald to pursue my PhD, in which I will study potential biomarkers of Parkinson’s disease using magnetic resonance imaging.
4W9A0365_web2Erind Alushaj: I completed my MSc in Neuroscience under the co-supervision of Dr. Penny MacDonald (PI), Dr. Ali Khan, and Dr. Adrian Owen. My research focused on differentiating the effects of early-stage Parkinson’s disease on the substantia nigra and ventral tegmental area. We used magnetic resonance imaging to segment these nuclei, detect changes in brain iron levels, and test their efficacy as diagnostic tools. I am now conducting a study looking to uncover preclinical biomarkers of Parkinson’s disease in patients with REM Sleep Behaviour Disorder (RBD), which will form the basis for my PhD in Neuroscience in the lab. 
Dimuthu Hemachandra: I am a Ph.D. student in the School of Biomedical Engineering at UWO. I completed my undergraduate degree in Physics from the University of Peradeniya in Sri Lanka and I obtained my MSc. in Astrophysics from the University of Western Ontario. My current research project is focused on analyzing the structural connectivity of the brain using Diffusion MRI to find a biomarker for Parkinson’s disease. I am co-supervised by Dr. Ali Khan & Dr. Penny MacDonald  
Maggie Prenger: I am a MSc Neuroscience student under the co-supervision of Dr. Penny MacDonald and Dr. Adrian Owen. I am primarily interested in how emotion processing and social cognition are affected by Parkinson’s disease. Using functional magnetic resonance imaging and electromyography, we are investigating the role of brain and facial muscle activity in emotion recognition. We are also looking at brain activity during the comprehension and appreciation of jokes. The results of these investigations will inform about the role of dopamine in brain regions responsible for important social processes. We will also gain knowledge regarding the relatively understudied emotional and social symptoms of Parkinson’s disease, and how best to treat these symptoms.  
Oren Princz-Lebel: I am completing a MSc in Neuroscience under the co-supervision of Dr. Penny MacDonald, Dr. Tim Bussey & Dr. Lisa Saksida. I am interested in the neuropathology that underlies cognitive impairments in psychiatric and neurodegenerative diseases. My research focuses on exploring the role of the dorsal and ventral striatum in stimulus-response learning, and how these regions are affected in disease states like Parkinson’s. We are using pharmacological, behavioural and optogenetic techniques in animal models to gain a better understanding of the mechanisms that drive this process and in hopes of providing new avenues for treatment and diagnosis in the clinic.  
Madeline Gilchrist: MSc 2019-2021.  To be completed.  
Brittany Hayes: MSc 2017-2019.    

Post-docs

Kasey Van Hedger: I am joining Dr. Penny MacDonald’s lab as a postdoc in the summer of 2018 to pursue my research interests in the neural, cognitive, and behavioral effects of psychiatric disorders. I began my research career as an undergraduate at Smith College where I worked on projects assessing hazardous alcohol use and drinking games participation among high school and college students with Byron Zamboanga. I completed my PhD in 2015 at the University of Chicago studying the psychophysiology of time perception with Greg Norman, and have spent the past three years as a postdoc in the Human Behavioral Pharmacology Lab working with Harriet de Wit. I am interested in psychophysiology, neuropsychopharmacology, and neuroimaging, particularly as each contributes to our understanding of substance use disorders.  (BrainsCAN Post-doctoral Fellow 2019-2022)

Associates

Mimma Annello: I am a third year Neurology resident doctor under the supervision of Dr.Penny Macdonald. I am interested in Parkinson’s disease and I am involved in multiple projects within the Macdonald lab. I previously worked with with Dr. Adrian Owen and Dr. Melvyn Goodale at The Brain and Mind Institute during my undergraduate degree and medical school training . I completed my undergraduate degree in Medical Science, and my medical school training both at Western University. I hope to do a fellowship in movement disorders and continue to pursue my interest in research.    
4W9A0350_web2Ozhand Ganjavi: To be completed  

 

Collaborators

Internal

  • Adrian Owen
  • Mel Goodale
  • Ali Khan
  • Tim Bussey
  • Lisa Saksida
  • Brian Corneil
  • Mark Daley
  • Frank Prato
  • Lena Palaniyappan
  • Stefan Kohler
  • Richard Kim
  • Jessica Grahn
  • Mandar Jog: UWO – Schulich School of Medicine & Dentistry
  • Mary Jenkins: UWO – Schulich School of Medicine & Dentistry
  • Hooman Ganjavi: UWO – Schulich School of Medicine & Dentistry
  • Daniel Mendonca
  • Jennifer Barr: UWO – Schulich School of Medicine & Dentistry
  • Marcus Povitz: UWO – Schulich School of Medicine & Dentistry
  • Alia Kashgari: UWO – Schulich School of Medicine & Dentistry
  • Michael Mak: UWO – Schulich School of Medicine & Dentistry

External

Trainees: Current & Past

Current Undergraduate Thesis Students

  • Racheal Madray (2019-2020)

Western Work-Study Program

  • Jeffrey Liang (2018-2019)

Research Assistant

  • Ivan Witt

Current Volunteers

  • Jackshani Jeevaretnam
  • Azmi Agha
  • Lydia Lauzon
  • Racheal Madray
  • Roja Ahimsadasan
  • Tarannum Khan
  • Mohammad Omer

Lab Alumni

Post-docs

  • Yoshiko Yabe, PhD

Graduate Students

  • Nicholas Handfield-Jones, MSc (August 2019)
  • Erind Alushaj, MSc (August 2019)
  • Shiny Yang, MSc
  • Nole Hiebert, MSc, PhD (completed both degrees in the lab, UWO Medical School, Class of 2022)
  • Daniel Glizer, MA
  • Kate Merritt, MSc (UOttawa Medical School, Class of 2022)
  • Brian David Robertson, MSc (UWO Medical School)

Thesis Students

  • Jessica Chuchin (Graduate Student, Ryerson University, Fall 2019)
  • Cleo Davies-Chalmers
  • Audrey Cullis
  • Rita Gustainis
  • Marc Lawrence (Medical School @ University of Ottawa)
  • Brian Lauzon (McMaster University, Michael G. DeGroote School of Medicine)
  • Lauren Chan (Medical School @ Western University, Class of 2023)
  • Marc Manzo
  • Collier Jiang (Medical School @ UofT)
  • Halley Gallant
  • Shiny Yang
  • Alyson Zwicker (Grad student, Pathology, Dalhousie University)
  • Jeffrey Lam
  • Omer Dost, MD (Resident Physician – Alberta Health Services)
  • Alexander Yan (MD/PhD student, UWO)
  • Allyson Partridge
  • Brian Robertson
  • Andrew Vo

Other Undergrad Research Electives/Courses

  • Lauren Chan (Medical School @ Western University, Class of 2023)
  • James Joon-Hyuck Im
  • Shreya Roy  (Medical Student Research Elective)
  • Cody Van Valkenburg, MD (Medical Student Research ElectiveUWO, Class of 2018)
  • Stephanie Solcz (Medical Student Research Elective)

Visiting Students

  • Wannipat Buated, PT, BME, PhD (Japan)

Medical Residents (Research Electives)

  • Mimma Anello (Neurology, UWO)

Schulich Research Opportunities Program

  • Rajas Tipnis (Medical Student, UWO)

NSERC Summer Students

  • Kelvin Zhou (2018) (Class of 2021 @ Michael G. DeGroote School of Medicine, McMaster University)

PEL Co-op Placement

  • Jack Bai (2018, A.B. Lucas Secondary School)
  • Alice Sung (2018, A.B. Lucas Secondary School)

Western Work-Study Program

  • Jessica Chuchin (2017-2019)
  • Jeffrey Liang (2018-2019)

Volunteers

  • Ravneet Nagra
  • Nikil Patil

Former Research Assistants

  • Alex A. MacDonald, MD (UofT Class of 2018, UWO Psychiatry Resident (2018-2023))
  • Ruzbeh Tamjeedi, LL.B
  • Stephanie Solcz, MD (UWO, Class of 2015)
  • Allison Berger

Note: Current status not available for all former students.